Arrested Development

Neurodegeneration: A Case of Arrested Development?

The neurodegenerative disease Spinocerebellar ataxia type 1 (SCA1) is a polyglutamine expansion disorder characterized by the death of Purkinje neurons in the brain. In this issue, Serra et al. (2006) implicate the impaired function of the orphan nuclear receptor RORalpha in SCA1 pathogenesis. Their intriguing results suggest that derailing a transcription program during embryonic development m...

Arrested pneumatization: witness of paranasal sinuses development?

OBJECTIVES Recent radiological studies have demonstrated that formation of the sphenoid sinus is preceded by a phase of fatty transformation of the bone marrow, and then by a phase of fat involution prior to the appearance of an aerated cavity and that this process can sometimes be interrupted, resulting in the persistence of images of arrested pneumatisation. The objective of the study was to ...

Health care in "arrested development": Naylor.

Federal health information policy: a case of arrested development.

Computerized patient records (CPRs) have reached a state of technical maturity that makes them an essential component of modern patient care. However, because uniform technical standards do not exist, CPRs constructed by different vendors do not convey clinical information easily from provider to provider. Moreover, unequal access to capital may mean a two-tier clinical information environment ...

Impaired Speechreading Related To Arrested Development of Face Processing

Childhood prosopagnosia is a rare disorder of face recognition consisting in the loss of one or more aspects of normal visual processing for faces as a consequence of a brain injury not present at birth. The paper reports on the case of patient, RP, a child prosopagnosic who sustained a closed head injury at age 7. Different aspects of speechreading ability are examined both with static and dyn...